Research Handling Guidance

Before reconstitution, allow both the lyophilised peptide and your chosen diluent to settle at normal laboratory room temperature. Equalising temperatures in this way supports the structural stability of the compound while it goes into solution.

Diluents and reconstitution solutions are purchased separately.

Research compound

TB-500

Name: TB-500
Brand: Regent Peptides
SKU: tb-500
Availability: InStock

£24.15/ 5mg vial

Dosage

Synthetic thymosin beta-4 fragment (Ac-LKKTETQ)

TB-500 is a synthetic peptide corresponding to the actin-binding region of thymosin beta-4 (Tβ4), a naturally occurring 43-amino-acid protein present in most cells. The supplied heptapeptide, N-acetyl-Leu-Lys-Lys-Thr-Glu-Thr-Gln, represents residues 17–23 of Tβ4 and is the segment responsible for G-actin sequestration in the literature.

Regent Peptides supplies TB-500 as a lyophilised powder in 5 mg and 10 mg vials, UK manufactured and independently tested batch by batch. The Certificate of Analysis for each batch is available via the lab reports page.

Research applications include actin dynamics and cell migration assays, wound-model work in cell culture and animal systems, and comparative or combined studies with BPC-157. Laboratory research use only.

Order before 3pm for same-day UK dispatch on Royal Mail Tracked 24, from £4.99.

Independent testing

All lab reports

HPLC and mass spectrometry on every batch. Certificate of Analysis available on request.

Third-party analysis by Janoshik Analytical. Each certificate is verifiable on the laboratory’s own site.

Manufactured and lyophilised in the UK
Plain, tracked packaging from £4.99
For laboratory research use only

Research Handling Guidance

Diluents and reconstitution solutions are purchased separately.

Technical data

Identity

Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
Sequence length: 7 amino acids (Tβ4 17–23)
Molecular formula: C38H68N10O14
Molecular weight: ≈ 889.0 g/mol
Form: Lyophilised powder, sealed vial

Identification

Product Name: TB-500
Catalogue Number: tb-500-5mg
Presentation: 5mg per vial

Physical & Chemical Properties

Appearance: White to off-white lyophilised powder
Purity: ≥99% by RP-HPLC
Identity: Confirmed by mass spectrometry
Solubility: Readily soluble in bacteriostatic or sterile water

Research Use & Safety

Intended Use: For laboratory research use only. Not for human or veterinary use.
Caution: Handle using appropriate PPE and in compliance with relevant laboratory safety standards.

Storage, Handling & Stability

Storage Temperature, Unopened: -20 °C recommended for long-term storage
Storage Temperature, Opened: -20 °C, minimise freeze-thaw cycles
Shelf Life: 2 years unopened under recommended conditions
Reconstitution Stability: Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions
Batch / Lot: Supplied on the batch Certificate of Analysis

For in-vitro laboratory research use only. Not a medicinal product. Not for human, veterinary, diagnostic, therapeutic or in-vivo use.

TB-500 questions

Is TB-500 the same as thymosin beta-4?

Not quite. Thymosin beta-4 is the full 43-amino-acid protein. TB-500 is the synthetic seven-residue fragment (17–23) that contains its actin-binding motif, which is why the two names are often used interchangeably in supplier listings.

How is TB-500 tested?

Each production batch is sent for independent HPLC purity analysis and mass spectrometry identity confirmation by Janoshik Analytical. The batch reference printed on the vial links to its Certificate of Analysis, which can be viewed on the lab's own verification site.

How is TB-500 supplied?

As a sterile lyophilised (freeze-dried) powder in a sealed glass vial, available in 5 mg and 10 mg vials. Vials are labelled with compound name, strength and batch reference and are dispatched in plain, tracked packaging from the UK.

How should the lyophilised vial be stored?

Unopened lyophilised vials should be kept refrigerated at 2–8 °C, or at −20 °C for long-term storage, protected from light. Once reconstituted, solutions should be refrigerated and used within the period appropriate to the laboratory's own stability data.

Is this for human use?

No. All Regent Peptides products are supplied strictly for in-vitro laboratory research. They are not medicines and are not for human or veterinary use, diagnosis or treatment.

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