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RegentPeptides
RegentPeptides

For research use only. Not for human consumption.

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RETATRUTIDE research vial by Regent Peptides

Research compound

Retatrutide

£60.00/ 10mg vial

Dosage

Triple GIP / GLP-1 / glucagon receptor agonist, 39 amino acids

Retatrutide (LY3437943) is a synthetic 39-amino-acid peptide designed to act at three receptors: GIP, GLP-1 and glucagon. Like tirzepatide it carries a fatty-diacid side chain that extends its half-life, but the addition of glucagon receptor activity distinguishes it in the literature as a 'triple agonist' and makes it the subject of some of the most-cited metabolic research currently being published.

We supply retatrutide as a lyophilised powder in sealed vials across six strengths. Every batch is manufactured in the UK and released against an independent HPLC purity result and mass spectrometry identity confirmation from Janoshik Analytical; the batch number on the label is searchable on our lab reports page.

Published research on retatrutide concentrates on multi-receptor incretin signalling, hepatic and adipose energy metabolism in preclinical models, and head-to-head comparison with dual and single agonists. Supplied strictly for laboratory research use.

Order before 3pm for same-day UK dispatch on Royal Mail Tracked 24, from £4.99.

Independent testing

All lab reports

Third-party analysis by Janoshik Analytical. Each certificate is verifiable on the laboratory’s own site.

  • Manufactured and lyophilised in the UK
  • Plain, tracked packaging from £4.99
  • For laboratory research use only

Research Handling Guidance

Before reconstitution, allow both the lyophilised peptide and your chosen diluent to settle at normal laboratory room temperature. Equalising temperatures in this way supports the structural stability of the compound while it goes into solution.

Diluents and reconstitution solutions are purchased separately.

Reconstitution reference

Concentration after adding diluent

Concentration
5 mg / ml
Concentration in micrograms
5,000 mcg / ml

Reference for laboratory preparation of lyophilised material only. Add diluent slowly down the inside of the vial and swirl gently; do not shake. Not administration guidance; for research use only.

Technical data

Identity

Sequence length
39 amino acids
Molecular formula
C221H342N46O68
Molecular weight
≈ 4,731 g/mol
Classification
GIP/GLP-1/glucagon triple receptor agonist
Form
Lyophilised powder, sealed vial

Identification

Product Name
Retatrutide
Catalogue Number
retatrutide-10mg
Presentation
10mg per vial

Physical & Chemical Properties

Appearance
White to off-white lyophilised powder
Purity
≥99% by RP-HPLC
Identity
Confirmed by mass spectrometry
Solubility
Readily soluble in bacteriostatic or sterile water

Research Use & Safety

Intended Use
For laboratory research use only. Not for human or veterinary use.
Caution
Handle using appropriate PPE and in compliance with relevant laboratory safety standards.

Storage, Handling & Stability

Storage Temperature, Unopened
-20 °C recommended for long-term storage
Storage Temperature, Opened
-20 °C, minimise freeze-thaw cycles
Shelf Life
2 years unopened under recommended conditions
Reconstitution Stability
Stable for up to 28 days at 2–8 °C in aqueous solution under sterile conditions
Batch / Lot
Supplied on the batch Certificate of Analysis

For in-vitro laboratory research use only. Not a medicinal product. Not for human, veterinary, diagnostic, therapeutic or in-vivo use.

Retatrutide questions

How does retatrutide differ from tirzepatide?
Both are 39-amino-acid peptides with GIP and GLP-1 receptor activity. Retatrutide additionally activates the glucagon receptor, which is the focus of most research comparing the two.
How is retatrutide tested?
Each production batch is sent for independent HPLC purity analysis and mass spectrometry identity confirmation by Janoshik Analytical. The batch reference printed on the vial links to its Certificate of Analysis, which can be viewed on the lab's own verification site.
How is retatrutide supplied?
As a sterile lyophilised (freeze-dried) powder in a sealed glass vial, available in six vial strengths. Vials are labelled with compound name, strength and batch reference and are dispatched in plain, tracked packaging from the UK.
How should the lyophilised vial be stored?
Unopened lyophilised vials should be kept refrigerated at 2–8 °C, or at −20 °C for long-term storage, protected from light. Once reconstituted, solutions should be refrigerated and used within the period appropriate to the laboratory's own stability data.
Is this for human use?
No. All Regent Peptides products are supplied strictly for in-vitro laboratory research. They are not medicines and are not for human or veterinary use, diagnosis or treatment.

Research context

Areas of published literature in which Retatrutide is studied. Educational reference only; no administration guidance is provided.

  • Multi-receptor incretin signalling
  • Hepatic and adipose energy metabolism
  • Glucagon receptor pharmacology
  • Comparative agonist studies

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